A Source of Relief for PMS
In 1983 a medical doctor, D.W. Remington, and his
associate, Robert Gardner, Ph.D., began researching hormone supplements
attempting to determine and solve the underlying causes of PMS.
They administered serial dilutions of Estrogen and
Progesterone sublingually. These were found to neutralize PMS and other
cyclical symptoms. Even chronic PMS symptoms were relieved, sometimes
dramatically.
A problem, however, arose in finding a neutralizing dose.
The effective dose often changed, requiring constant monitoring and
adjustments for each patient.
Their proposed Symptom Relief was to initiate hormone treatment at a high concentration and progressively move to lower concentrations.
Many patients realized positive results with this system;
however, the results were unpredictable. At times, patients would react
negatively to a concentration that had formerly controlled symptoms. The
team began researching methods to deliver treatment that would
stabilize the patient on one dosage amount for extended periods of time.
Imagine their surprise when they discovered that the most
stable results were realized only when the dilutions reached homeopathic
levels!
Their labors led them to the development of Hormone
Combination. This product includes a group of hormones in multiple
homeopathic dilutions administered together (called a homochord) -a
combination that was found to clear symptoms each time, as well as
stabilize the patients long-term.
Hormone Combination made it possible to administer a standard dose to each patient with confidence in the expected outcome.
Why it Works
At first, it was assumed that the right concentration of
the combined hormones somehow stopped or shut off an inappropriate
immune response to the hormone. Further perspective indicated that
Hormone Combination works through other systems in addition to affecting
the immune system.
A double-blind study was performed using tryptophan (an
amino acid), nicotinamide (a B vitamin), imipramine or a
tryptophan-nicotinamide-imipramine. This combination given to severely
depressed people helped provide further understanding as to why Hormone
Combination works.
Observations showed that some doses of
tryptophan-nicotinamide-imipramine worked very well, but smaller or
larger doses did not. This was the effective dose range or "therapeutic
window." This window may really be the result of immune modulation or
regulation.
It was determined that immune modulation might apply to
body chemicals, microorganisms, substances in foods, and, in fact, to
all substances that find their way into the body. It has been observed
that many sensitive patients have an intolerance to serotonin,
epinephrine, progesterone, glucose and other substances that further
complicate their response to foods, pollens, chemicals and even
emotional stress.
This intolerance may result from the natural cycles in the
levels of hormones, food chemicals, etc., being outside the range the
immune system can handle. This could mean the cycling levels of hormones
are outside the tolerable "therapeutic window" dictated by immune
modulation.
Hormone Combination appears to have the effect of widening
the permissible range in which the natural cycles of changing hormone
amounts in the system can operate without symptoms.
As mentioned, women can experience improvements so quickly
from taking Hormone Combination that the next menstrual cycle may occur
with no symptoms or warnings. For a few, the first cycle following
administration of Hormone Combination can involve changes -even slight
worsening - of some symptoms. When this happens, the second cycle will
generally be much improved. No adverse side effects from the Symptom Relief
have been reported.