Uses For Biotin
Nutrient Metabolism: Biotin forms a covalent
bond to the following carboxylase enzymes: pyruvate carboxylase for
glucose metabolism, acetyl CoA carboxylase for fatty acid oxidation, and
propionyl-CoA carboxylase and b-methylcrotonyl-CoA carboxylase for
amino acid metabolism. One double-blind study reported that biotin
supplementation may promote healthy lipid metabolism. Another clinical
study reported that high dose administration of biotin helped promote
healthy glucose metabolism. A number of animal studies support this
claim. Biotin may also act to promote transcription and translation of
glucokinase, an enzyme found in the liver and pancreas that participates
in the metabolism of glucose to form glycogen. Recent studies have
expanded biotin's metabolic role, claiming that the vitamin maintains
healthy genetic expression of the many enzymes for which it is a
cofactor. One study suggested that this gene modulation is supportive of
healthy immune system function, stating that biotin may be involved in
the transcription of some immune cells.*
Nerve Function: Optimal levels of biotin are
supportive of nervous system health and function. A clinical study
indicates that biotin promotes nerve cell health.*
Nail Health: Clinical studies indicate that
biotin may adjust the cellular arrangement of the nail bed, helping to
reinforce the keratin structure, promote strength and thickness, and
reduce splitting.*
What Is The Source?
Biotin is synthetic. Hypo-allergenic plant fiber is derived from pine cellulose.
Suggested Use:
1–2 capsules daily, in divided doses, with meals.
If pregnant or lactating, consult your physician before
taking this product. At this time, there are no known side effects or
precautions. Consult your physician for more information.
There is one case of eosinophilic pleuropericardial effusion
with high-dose biotin 10 mg per day in combination with pantothenic acid
300 mg for 2 months, however it is not known if this was a result of
the supplementation. Consult your physician for more information.