Folate deficiency linked to tripled risk of dementia:
A newly published study shows a lack of folate, also called folic acid or vitamin B-9, may triple the risk of developing dementia in old age.
Researchers measured naturally occurring folate levels in 518 elderly persons, none of whom showed any signs of dementia, and then tracked their development over 2.4 years. At the end of the period, 45 of the patients had developed dementia, including 34 diagnosed with Alzheimer's disease, said the study, published by the British Medical Association's Journal of Neurology, Neurosurgery and Psychiatry.
Even after other factors were taken into account -- including age, disability, alcohol consumption, weight change -- "the onset of dementia was significantly associated with an exaggerated decline in folate," the researchers concluded.
In another study published last year in The Lancet showed an improvement in short-term memory, mental agility and verbal fluency among persons over 50 who took a daily dose of 800 micrograms (mcg) of folic acid. The US recommended daily dose is 400 mcg.
Folic acid is a water-soluble B vitamin. Its derivatives act as coenzymes responsible for regulating several aspects of cellular metabolism and is essential for the creation of new cells in the body. The compound occurs naturally in leafy vegetables such as spinach, turnip greens, lettuces, dried beans and peas and in certain fruits.
Supplementing with 1000 micrograms of folic acid in addition to eating a healthy diet rich in green leafy vegetables can help reduce the risk of dementia later in life.
Please make sure your daily supplement contains adequate amounts of folic acid and other key nutrients in forms that are bioavailable.
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